| Father | Daniel D. Griffith (1812 - 1886) |
| Mother | Ann Eliza Trotter (1818 - 1901) |
| Sibling | James Allison Griffith Sr. (1834 - 1910) |
| Sibling | George Griffith ( - ) |
| Sibling | Joseph Franklin "Frank" Griffith (1839 - 1898) |
| Sibling | John F. "Morten" Griffith (1842 - ) |
| Sibling | Sarilda Carlsa "Zerilda" "Lorilda" Griffith (1845 - 1927) |
| Sibling | Madison Emsley Griffith (1847 - 1903) |
| Sibling | Louisa Rebecca Griffith (1850 - 1913) |
| Sibling | Jasper Newton "Newt" Griffith (1851 - 1936) |
| Sibling | Christopher Colombus Griffith (1854 - 1934) |
| Sibling | Jemima Juliana "Narcissus" Griffith (1858 - 1926) |
| Sibling | Julia "Julie" Ann Griffith (1862 - 1900) |