| Spouse | Sir William de Laird Seton (1390 - 1424) |
| Child | Margaret Seton (1294 - ) |
| Child | Marion Seton (1404 - 1467) |
| Child | George JOHNSTONE (1406 - 1478) |
| Child | Janet Seton (1410 - 1493) |
| Child | Janet JOHNSTONE (1412 - ) |
| Child | Lady Catherine Seton Countess Darnley (1414 - 1478) |
| Child | George De Seton (1416 - 1478) |
| Child | Marian Seton (1416 - 1447) |
| Child | Margaret Johnstone (1418 - ) |
| Child | Janet Seton (1429 - 1525) |
| Child | Matthew Westerhall Johnstone (1430 - ) |
| Child | Laurence Johnstone (1430 - ) |
| Child | Archibald Johnstone (1430 - 1492) |
| Child | Thomas Breconside Johnstone (1430 - ) |
| Child | Elizabeth Johnston (1430 - 1530) |
| Child | Patrick Johnstone (1435 - ) |
| Child | Gilbert Johnstone (1439 - 1501) |
