| Father | Sir William de Laird Seton (1390 - 1424) |
| Mother | Janet Dunbar (1390 - 1434) |
| Sibling | Margaret Seton (1294 - ) |
| Sibling | George JOHNSTONE (1406 - 1478) |
| Sibling | Janet Seton (1410 - 1493) |
| Sibling | Janet JOHNSTONE (1412 - ) |
| Sibling | Lady Catherine Seton Countess Darnley (1414 - 1478) |
| Sibling | George De Seton (1416 - 1478) |
| Sibling | Marian Seton (1416 - 1447) |
| Sibling | Margaret Johnstone (1418 - ) |
| Sibling | Janet Seton (1429 - 1525) |
| Sibling | Matthew Westerhall Johnstone (1430 - ) |
| Sibling | Laurence Johnstone (1430 - ) |
| Sibling | Archibald Johnstone (1430 - 1492) |
| Sibling | Thomas Breconside Johnstone (1430 - ) |
| Sibling | Elizabeth Johnston (1430 - 1530) |
| Sibling | Patrick Johnstone (1435 - ) |
| Sibling | Gilbert Johnstone (1439 - 1501) |