| Spouse | Charles Thompson (1774 - 1851) |
| Child | Seaborn J. Thompson (1806 - 1876) |
| Child | Louisa Thompson (1807 - ) |
| Child | Thomas B. Thompson (1809 - ) |
| Child | Hilliard Judge Thompson (1813 - 1881) |
| Child | Mary Ann Thompson (1816 - 1859) |
| Child | Martha Adeline Thompson (1817 - 1841) |
| Child | John C. Thompson (1820 - ) |
| Child | William H. Thompson (1821 - ) |
| Child | Virgil Vivian Thompson (1822 - 1902) |
| Child | Charles Jasper Thompson (1829 - 1858) |
| Child | Margaret Thompson (1830 - ) |
| Child | Joseph Lafayette Thompson (1831 - ) |
| Child | Robert E. Thompson (1834 - ) |