Individual Details

One WorldConnect database has his birth as 26 Feb 1784.

His prenuptial agreement with the second wife, Mary R. Turner, was that she receive at his death, a part of his estate equal to that of his ten children. He stated his two youngest, William and Samuel, had not had any advancements.

1850 Census. Goochland Co, VA Hh 85
William Hopkins, age 65, Farmer, property value $23,000. b. VA
Mary R., 37.
Samuel A., 22, manager of farm
Hh86
Nathaniel M. Hopkins, age 32, farmer. Lucy Anne, 31
Sarah E. 6, Thomas B. 4, Araminta C., 3, Zachry Taylor, 1
Wm. J. Hopkins, age 25

There were numerous lawsuits following his death.
The Commissioner's Notice in a local newspaper contained names of his heirs, 15 May 1869.
Circuit Court, Louisa Co VA
The plaintiffs were:
Mary R. Hopkins [presumably the widow]
John H. M. Hopkins
Elizabeth McDearman, wife of James A. McDearman [dau of Wm & Sallie]
Mary Ann Ware, wife of Richard Ware [dau of Wm & Sallie]
Rosa Bolling and Blair Bolling
Wm. J. Hopkins [prob son of Wm & Sallie]
Samuel A. Hopkins [son of Wm & Sallie]
Nathaniel Hopkins [son of Wm & Sallie]
N. H. Page
Samuel H. Haden
Defendants:
Benjamin F. Rhodes & Helena B., his wife [dau of Wm & Sallie]
Edward C. Turner & Caroline, his wife [dau of Wm & Sallie]
A. M. Hamilton, sheriff of Goochland, as admin of John J. Mathews, dec'd; Emily Mathews, dec'd; Virgilias L. W. Mathews, dec'd; and of Edward Mathews, dec'd
Edward Mathews in his own right and trustee for children of Charlotte Mathews, dec'd
Charles Massie, executor of Wm Hopkins [presumably this man]
Walter D. Leake
John H. Guy
A. C. Page
Julian Harrison
Miletus T. Gooch, sherrif of Louisa and admin of William Bolling, dec'd

One of the sheets in the court file on Library of Virginia website shows a payout to eight heirs of William Hopkins.
John H. Guy had collected of Julius Harrison, on 17 Nov 1870 the amount of $700 and after expenses $679.16 was distributed in equal parts to:
Mary F. Hopkins [plainly F, not R]
Benj F. Rhodes in right of his wife Helen
Edwd C. Turner in right of his wife Caroline
Edwd Mathews trustee for Charlotte Mathews' children
Saml. A. Hopkins trustee for J. H. M. Hopkins
J. H. M. Hopkins as trustee for Eliz. McDearman
and for Sarah Bolings children
and for Mary A. Ware
Note: The prenuptial had specified 10 children and the widow to receive equal shares so three appear to be missing from the above list. There are no payments to William H and Nathaniel Hopkins who I definitely believe were sons - and Saml. A. received no share for himself. Those three would bring the total to 11 heirs.

Birth	Ca 1785	Goochland County, Virginia
Marriage	14 Nov 1849	Albemarle County, Virginia - Mary Rachel Turner
Marriage		Sallie Massey

Spouse	Sallie Massey (1790 - )
Child	Helena B. Hopkins ( - )
Child	Charlotte Hopkins (1809 - 1860)
Child	Mary Ann Hopkins (1810 - )
Child	John H. M. Hopkins ( - )
Child	Sarah Hopkins (1816 - )
Child	Nathaniel Hopkins (1818 - )
Child	Elizabeth Miller Hopkins (1819 - 1889)
Child	Caroline Hopkins (1824 - )
Child	William J. Hopkins (1825 - )
Child	Samuel A. Hopkins (1828 - )

Spouse

Mary Rachel Turner (1813 - )

Father	John Hopkins (1726 - 1807)
Mother	Mary Martin ( - )