| Birth | 1805 | | | | |
| Education | | at the Troy Female Seminary (now known as Emma Willard School) - Troy, Rensselaer County, New York | | | |
| Miscellaneous | 1821 | met William Henry Seward through his sister (Frances' classmate) - New York | | | |
| Marriage | 20 Oct 1824 | Auburn, Cayuga County, New York - William Henry SEWARD Sr. | | | |
| Residence (family) | From 20 Oct 1824 to 10 Oct 1872 | in the Seward House (built by his father-in-law, Elijah Miller, in 1816) - Auburn, Cayuga County, New York - William Henry SEWARD Sr. | | | |
| Residence (family) | 19 Jul 1850 | with Frances' father, Elijah Miller, - Auburn, Cayuga County, New York - William Henry SEWARD Sr. | | | |
| Miscellaneous | | along with sisters Martha Coffin Wright & Lucretia Coffin Mott encouraged Harriet Tubman to reside - Auburn, Cayuga County, New York | | | |
| Illness | 14 Apr 1865 | severe anxiety after Lewis Powell (aka Lewis Paine) attempted to assassinate William in their house - Auburn, Cayuga County, New York | | | |
| Death | 21 Jun 1865 | of a heart attack - Auburn, Cayuga County, New York | | | |