| Father | Mitchell Clay (1736 - 1811) |
| Mother | Phoebe Belcher (1742 - 1810) |
| Sibling | David Clay (1761 - 1818) |
| Sibling | Tabitha Clay (1763 - 1783) |
| Sibling | Bartley Clay (1766 - 1783) |
| Sibling | Ezekiel Clay (1767 - 1783) |
| Sibling | Rebecca Clay (1769 - 1844) |
| Sibling | Mitchell Clay (1769 - 1851) |
| Sibling | Mary Obedience Clay (1771 - 1856) |
| Sibling | John Clay (1771 - 1783) |
| Sibling | Patience Clay (1772 - 1812) |
| Sibling | Nannie Clay (1773 - ) |
| Sibling | William Mitchell Clay (1777 - 1842) |
| Sibling | Henry J Clay (1781 - 1866) |
| Sibling | Sarah Clay (1783 - ) |
| Sibling | Polly Clay (1789 - ) |
