| Father | Eli Bradshaw WEDDINGTON (1792 - 1864) |
| Mother | Margaret PALMER (1798 - 1868) |
| Sibling | John Palmer "J. P." WEDDINGTON (1817 - 1891) |
| Sibling | Sarah R. WEDDINGTON (1819 - 1877) |
| Sibling | Cynthia L. WEDDINGTON (1822 - 1840) |
| Sibling | Mary Eliza WEDDINGTON (1824 - 1886) |
| Sibling | Helena B. WEDDINGTON (1827 - 1902) |
| Sibling | Minerva Emeline WEDDINGTON (1829 - 1854) |
| Sibling | Dr. Andrew B. WEDDINGTON (1833 - 1894) |
| Sibling | Jane WEDDINGTON (1835 - 1866) |
| Sibling | Margaret Caroline "Callie" WEDDINGTON (1837 - ) |
| Sibling | Dr. Rufus A. WEDDINGTON (CSA) (1840 - 1927) |
| Sibling | Frank J. WEDDINGTON (1842 - 1856) |