| Spouse | Sir John 2nd Lord Seton (1370 - 1434) |
| Child | Sir William de Laird Seton (1390 - 1424) |
| Child | Christian Seton (1392 - ) |
| Child | Alexander Seton (1393 - ) |
| Child | Janet Seton (1395 - ) |
| Child | Roger Seton (1395 - ) |
| Child | Margaret Seton (1397 - ) |
| Child | Marian Seton (1397 - ) |
| Child | Jean Seton (1401 - ) |
| Child | John DeSeton (1403 - 1424) |
| Child | Alexander DeSeton (1404 - ) |
| Child | Catherine Seton (1405 - ) |
| Child | Jean DeSeton (1407 - ) |
| Child | Anna Seton (1407 - ) |
| Child | Lucy Seton (1409 - ) |
| Child | Marian Seton (1409 - 1447) |
| Child | Christian Seton (1492 - ) |