| Spouse | Henry J. Jackson Sr (1763 - 1852) |
| Child | Ester Jackson (1801 - 1835) |
| Child | Elizabeth Permelia Jackson (1802 - 1862) |
| Child | William Vandeavater Jackson (1804 - ) |
| Child | Hyer Jackson (1806 - 1873) |
| Child | Edward Jackson (1808 - 1851) |
| Child | Henry J. Jackson Jr (1813 - 1865) |
| Child | Amanda Melvina Jackson (1816 - 1902) |
| Child | Rachael Cecelia Jackson (1817 - 1912) |
| Child | John Henderson Brake Jackson (1820 - 1869) |
| Child | Jacob Jackson (1821 - 1823) |
| Child | Ulysses Jackson (1824 - 1882) |
| Child | Mary Sophia Madelena Rosa Janis Jackson (1827 - 1906) |