| Spouse | Letitia "Letty" Dalton (1742 - 1838) |
| Child | John Moore (1758 - 1768) |
| Child | Matthew Moore (1760 - 1780) |
| Child | Ann "Nancy" Moore (1762 - 1848) |
| Child | Samuel Dalton Moore (1764 - 1854) |
| Child | Letitia Moore (1765 - ) |
| Child | Mary "Polly" Moore (1767 - 1863) |
| Child | Reuben Moore (1768 - 1817) |
| Child | Edward Moore (1770 - 1855) |
| Child | David Moore (1773 - 1783) |
| Child | William Moore (1775 - 1867) |
| Child | Elizabeth Moore (1777 - 1849) |
| Child | John Moore (1783 - ) |
| Child | Gabriel Moore (1785 - 1844) |
| Child | Tucker Woodson Moore (1785 - 1816) |
| Child | Matthew Redd Moore Jr. (1792 - 1877) |