| Father | Capt. James Sanford Pickett (1768 - 1852) |
| Mother | Nancy Smith ( - ) |
| Sibling | Patsy Winn Pickett (1801 - 1846) |
| Sibling | Albert Gallatin Pickett (1803 - ) |
| Sibling | Eliza Metcalf Pickett (1805 - ) |
| Sibling | William Sanford Pickett (1810 - 1884) |
| Sibling | Gustavus Adolphus Pickett (1813 - ) |
| Sibling | Sallie Catherine Pickett (1815 - 1856) |
| Sibling | Charles Edward Pickett (1817 - 1882) |
| Sibling | John Pickett (1820 - ) |
| Sibling | Rev. James Thomas Pickett (1823 - 1905) |
| Sibling | James Pickett (1825 - ) |
| Sibling | Mary Eloise Pickett (1831 - 1906) |