| Father | James Ballinger Machen (1773 - 1846) |
| Mother | Dorcas Payne (1765 - 1821) |
| Sibling | John Lewis Machen Sr. (1793 - 1883) |
| Sibling | Thomas Wood Machen (1794 - 1846) |
| Sibling | William Ballinger Machen (1796 - 1871) |
| Sibling | Henry Machen (1798 - 1860) |
| Sibling | Roland Machen (1799 - 1835) |
| Sibling | Frances Clementine Machen (1803 - 1860) |
| Sibling | Elizabeth Machen (1805 - 1870) |
| Sibling | Hannah Machen (1807 - 1844) |
| Sibling | Grace Greenwood Machen (1809 - 1870) |
| Sibling | James L. Machen (1810 - ) |
| Sibling | Mary Machen (1812 - 1844) |
| Sibling | Nancy Machen (1814 - 1894) |
