| Spouse | Matteo Maurizio Libretti (1692 - 1776) |
| Child | Teodosio Arcangelo Nunziate Libretti (1722 - ) |
| Child | Rosa Cristina Libretti (1723 - 1724) |
| Child | Rosa Libretti (1725 - 1726) |
| Child | Diego Benedetto Libretti (1726 - 1799) |
| Child | Giacomo Libretti (1728 - 1729) |
| Child | Angelica Petronilla Annunziata Libretti (1730 - 1769) |
| Child | Perna Libretti (1731 - 1731) |
| Child | Angelo Giacomio Libretti (1733 - 1744) |
| Child | Dorotea Libretti (1735 - 1740) |
| Child | Rosaria Angelica Libretti (1737 - 1740) |
| Child | Carmine Mario Libretti (1740 - 1777) |
| Child | Anna Catarina Libretti (1743 - 1792) |
| Child | Crescentio Arcangelo Libretti (1745 - 1812) |