| Spouse | Thomas Henry Franklin PRATHER (1740 - 1820) |
| Child | Thomas Henry Franklin PRATHER Jr. (1784 - 1855) |
| Child | Elizabeth "Eliza" PRATHER (1786 - ) |
| Child | Mary "Polly" PRATHER (1786 - ) |
| Child | Eli PRATHER (1787 - 1812) |
| Child | John PRATHER (1787 - 1860) |
| Child | Sarah PRATHER (1788 - ) |
| Child | Philip PRATHER (1788 - 1850) |
| Child | Hiram Henry PRATHER (1796 - 1861) |
| Child | Eleanor "Nellie" PRATHER ( - 1840) |
| Child | Nathan Jeffros Franklin PRATHER (1800 - 1884) |
| Child | Elisha R. PRATHER (1804 - 1860) |
| Child | Hamilton Erwin PRATHER (1804 - 1840) |