| Spouse | Jacob Hoffman Hershey Senior (1824 - 1896) |
| Child | Frances M. Hershey (1845 - 1923) |
| Child | Simon Andrew Hershey (1847 - 1911) |
| Child | Amos Brenneman Hershey (1848 - 1897) |
| Child | Hershey (1850 - ) |
| Child | Rebecca A. Hershey (1851 - 1923) |
| Child | Barbara Amanda Hershey (1853 - 1858) |
| Child | Emma Susan Hershey (1855 - 1947) |
| Child | Mary Emma Hershey (1857 - 1939) |
| Child | Martha Jane Hershey (1858 - 1959) |
| Child | Abraham Lincoln Hershey (1861 - 1864) |
| Child | Barbara Alice Hershey (1863 - 1892) |
| Child | Jacob Hoffman Hershey Junior (1865 - 1886) |