| Father | James H. Dewitt Sr. (1744 - 1824) |
| Mother | Abigail Wilkerson (1748 - 1828) |
| Sibling | Walter Dewitt (1764 - ) |
| Sibling | Aaron Dewitt (1773 - 1827) |
| Sibling | Thomas Dewitt (1778 - ) |
| Sibling | Milly Dewitt (1779 - 1866) |
| Sibling | James Henry Dewitt Jr. (1780 - 1859) |
| Sibling | Jesse Dewitt (1782 - ) |
| Sibling | Permelia / Pamela Dewitt (1782 - ) |
| Sibling | Malinda Dewitt (1783 - 1860) |
| Sibling | John Ross Dewitt (1784 - 1878) |
| Sibling | Mary "Polly" Dewitt (1788 - ) |
| Sibling | Bennett Maxie DeWitt (1793 - 1840) |
| Sibling | Caleb Dewitt (1797 - 1846) |
| Sibling | Jeremiah T Dewitt (1799 - 1861) |
