| Father | Joseph Holcomb (1815 - 1903) |
| Mother | Elizabeth A. Widener (1823 - 1870) |
| Sibling | Savilla A. Holcomb (1840 - 1914) |
| Sibling | Calvin Hank Holcomb (1842 - 1861) |
| Sibling | Alvin Eubanks Holcomb (1842 - ) |
| Sibling | Elmina Holcomb (1848 - ) |
| Sibling | Moses Duke Holcomb (1848 - 1928) |
| Sibling | America Elmira Holcomb (1848 - 1917) |
| Sibling | Miles Butler Holcomb (1849 - 1910) |
| Sibling | Jesse Franklin Holcombe (1851 - ) |
| Sibling | Doctor Holcombe (1852 - ) |
| Sibling | John Clark Holcombe (1854 - 1898) |
| Sibling | Howard Holcombe (1856 - ) |
| Sibling | George Washington Holcomb (1858 - 1926) |
| Sibling | Mary C. Holcombe (1859 - ) |
| Sibling | Martha S. Holcombe (1862 - ) |
| Sibling | Nancy Holcombe (1864 - ) |