| Spouse | Dorothy TWEEDY (1572 - 1647) |
| Child | William BLAKE (1575 - 1642) |
| Child | Grace BLAKE (1588 - 1622) |
| Child | Richard BLAKE (1591 - 1667) |
| Child | Emma BLAKE (1592 - 1593) |
| Child | Mary BLAKE (1594 - 1613) |
| Child | William Giles BLAKE (1594 - 1663) |
| Child | John BLAKE (1597 - 1645) |
| Child | Charles BLAKE (1599 - ) |
| Child | Anne BLAKE (1600 - 1667) |
| Child | Thomas BLAKE (1600 - ) |
| Child | Arthur BLAKE (1600 - 1600) |
| Child | Richard BLAKE (1603 - 1650) |
| Child | Arthur BLAKE (1604 - ) |
| Child | Peter BLAKE (1605 - ) |
| Child | Elizabeth BLAKE (1609 - ) |
| Child | Martha BLAKE (1611 - 1613) |
| Child | Martha BLAKEBOROUGH 'BLAKE' (1612 - 1640) |
| Child | Dorothy BLAKE (1613 - 1702) |
| Child | Joanna BLAKE (1615 - 1667) |
| Child | Mary BLAKE (1617 - ) |
| Child | Anne "Annie" BLAKE-LEADER (1618 - 1681) |
| Child | Margaret BLAKE (1619 - 1613) |
| Child | William BLAKE (1620 - 1703) |