| Spouse | Elizabeth WHITEHEAD (1690 - 1746) |
| Child | Philip Whitehead CLAIBORNE (1720 - 1771) |
| Child | William CLAIBORNE (1721 - 1746) |
| Child | Elizabeth Ann CLAIBORNE (1722 - 1811) |
| Child | Lucy CLAIBORNE (1725 - 1810) |
| Child | Lucy Peg CLAIBORNE (1725 - 1810) |
| Child | Catherine CLAIBORNE (1725 - 1788) |
| Child | Philadelphia CLAIBORNE (1727 - 1765) |
| Child | Unity CLAIBORNE (1745 - 1816) |
| Child | Richard CLAIBORNE (1755 - ) |
| Child | Nathaniel CLAIBORNE (1755 - ) |
| Child | William 5 CLAIBORNE (1766 - 1845) |
| Child | Nathaniel Herbert CLAIBORNE (1777 - 1859) |
| Child | Mary Leigh CLAIBORNE (1781 - 1812) |