| Spouse | Elizabeth Ann DUVALL (1812 - 1893) |
| Child | Male LITTLETON (1835 - ) |
| Child | Charles LITTLETON (1836 - 1913) |
| Child | Thomas Loyd LITTLETON (1838 - 1915) |
| Child | William M. LITTLETON (1840 - 1900) |
| Child | Sarah Elizabeth LITTLETON (1841 - 1912) |
| Child | Clemuel B. LITTLETON (1843 - 1921) |
| Child | Clem LITTLETON (1843 - ) |
| Child | Jesse M. LITTLETON (1844 - 1898) |
| Child | Clement B. LITTLETON (1844 - 1921) |
| Child | Margaret LITTLETON (1846 - ) |
| Child | Nancy M. LITTLETON (1846 - 1920) |
| Child | Eliza J. LITTLETON (1847 - 1916) |
| Child | John Samuel LITTLETON (1848 - 1921) |
| Child | Mary M. PHELPS (1849 - ) |
| Child | Benjamin Franklin LITTLETON (1850 - 1923) |
| Child | Barbara LITTLETON (1851 - 1894) |
| Child | Reuben H. LITTLETON (1853 - 1889) |
| Child | Subia Ann LITTLETON (1857 - 1932) |