| Spouse | Catrina Catron (1730 - 1785) |
| Child | Thomas Melton (1720 - ) |
| Child | Elizabeth Melton (1721 - ) |
| Child | Mary Farr Melton (1724 - ) |
| Child | Joel Farr Melton (1728 - 1772) |
| Child | John Melton (1729 - 1813) |
| Child | Richard Melton (1729 - 1772) |
| Child | Silas Melton (1734 - 1783) |
| Child | Isaac Melton (1735 - ) |
| Child | John Melton (1753 - 1813) |
| Child | Mildred Melton (1755 - ) |
| Child | Benjamin Melton (1758 - 1810) |
| Child | Eady Melton (1762 - 1820) |
| Child | Joshua Melton (1766 - 1825) |
| Child | Cornelius Melton (1768 - 1821) |
| Child | Eleanor Melton (1775 - ) |
| Child | Living |