| Father | George DOWNING (1552 - ) |
| Mother | Dorcas BLOIS OR BELLAMY (1554 - ) |
| Sibling | Susan DOWNING ( - 1635) |
| Sibling | Joshua DOWNING (1580 - ) |
| Sibling | Abigail DOWNING (1580 - ) |
| Sibling | Nahomie DOWNING (1583 - ) |
| Sibling | Joseph DOWNING (1583 - 1656) |
| Sibling | Emanuel DOWNING (1585 - 1658) |
| Sibling | Nathaniel DOWNING (1587 - 1616) |
| Sibling | James DOWNING (1590 - ) |
| Sibling | Benjamin DOWNING (1593 - ) |
| Sibling | Joshua DOWNING (1593 - ) |
| Sibling | Susanna DOWNING (1593 - ) |
| Sibling | John DOWNING (1596 - ) |
| Sibling | Nahomie DOWNING (1597 - ) |
| Sibling | Dorcas DOWNING (1600 - ) |
| Sibling | George DOWNING (1604 - ) |
| Sibling | Elizabeth DOWNING (1606 - ) |
| Sibling | Anne DOWNING ( - ) |
| Sibling | Elnathan DOWNING (1597 - 1609) |