| Father | Dn. Alonso ENRÍQUEZ I Almirante de Castilla (1354 - 1429) |
| Mother | Juana GONZÁLEZ DE MENDOZA "La ricahembra de Guadalajara" (1360 - 1431) |
| Sibling | Don Fadrique ENRIQUEZ DE MENDOZA, ALMIRANTE DE CASTILLA (1390 - 1473) |
| Sibling | Aldonza ENRÍQUEZ DE MENDOZA (1373 - ) |
| Sibling | Maria ENRIQUEZ DE MENDOZA (1377 - ) |
| Sibling | Blanca ENRIQUEZ DE MENDOZA (1390 - 1448) |
| Sibling | Alonso ENRIQUEZ (1390 - ) |
| Sibling | Beatríz ENRÍQUEZ DE MENDOZA (1396 - 1439) |
| Sibling | Maria ENRIQUEZ Y MENDOZA DE CASTILLE (1398 - 1441) |
| Sibling | Constanza ENRÍQUEZ (1400 - ) |
| Sibling | Isabel ENRÍQUEZ DE MENDOZA (1402 - 1479) |
| Sibling | Inés ENRIQUEZ DE MENDOZA (1410 - ) |
| Sibling | Fray Juan ENRIQUEZ DE MENDOZA ( - 1418) |
| Sibling | Rodrigo ENRIQUEZ ( - 1465) |
| Sibling | Pedro ENRIQUEZ DE MENDOZA ( - 1486) |
| Sibling | Count of Alba de Liste Enrique ENRÍQUEZ DE MENDOZA ( - 1489) |
| Sibling | Leonor ENRÍQUEZ DE MENDOZA ( - ) |