| Father | John COTTON II (1436 - 1488) |
| Mother | Joanna FITZHERBERT (1446 - 1485) |
| Sibling | Sir Richard COTTON (1455 - 1497) |
| Sibling | Audrey COTTON (1454 - 1494) |
| Sibling | Catherine COTTON (1460 - 1507) |
| Sibling | James COTTON (1462 - ) |
| Sibling | Sir John COTTON III (1466 - ) |
| Sibling | Elizabeth COTTON (1469 - 1488) |
| Sibling | Richard COTTON (1470 - 1540) |
| Sibling | Walter COTTON (1472 - ) |
| Sibling | Roger Walter COTTON (1474 - ) |
| Sibling | John COTTON (1475 - 1534) |
| Sibling | Richard COTTON (1478 - 1534) |
| Sibling | Elizabeth COTTON (1481 - ) |
| Sibling | Ann COTTON (1484 - 1569) |
| Sibling | Elizabeth COTTON (1488 - 1569) |
| Sibling | Margaret COTTON ( - 1560) |
| Sibling | Edmund COTTON ( - ) |
| Sibling | Thomas COTTON ( - ) |
| Sibling | William COTTON ( - ) |