| Spouse | Lucinda Jane Tutor (1840 - 1915) |
| Child | John H. McGregor (1866 - 1870) |
| Child | Samuel Young McGregor (1867 - 1933) |
| Child | Mary Ann McGregor (1868 - 1927) |
| Child | William B. McGregor (1870 - 1870) |
| Child | James Gay McGregor (1871 - 1965) |
| Child | Willis S. McGregor (1872 - 1963) |
| Child | Nettie J. McGregor (1873 - 1874) |
| Child | Wiley Harrison McGregor (1875 - 1951) |
| Child | Rebecca Jane McGregor (1877 - 1907) |
| Child | Ezekial I. McGregor (1879 - 1880) |
| Child | Georgia Elizabeth McGregor (1881 - ) |
| Child | Alexander F. McGregor (1883 - 1887) |
| Child | Eddie McGregor (1885 - 1958) |