| Father | Sir Ralph de Neville 1st Earl of Westmorland ( - ) |
| Mother | Lady Joan de Beaufort (1379 - ) |
| Sibling | Lady Katherine de Neville Dutchess of Norfolk (1395 - 1483) |
| Sibling | Richard de Neville 5th Earl of Salisbury ( - ) |
| Sibling | William de Neville Earl of Kent (1403 - 1463) |
| Sibling | Geoffrey de Neville Lord Latimer (1405 - 1469) |
| Sibling | George Edward de Neville ( - ) |
| Sibling | Robert de Neville Bishop of Salisbury (1407 - 1457) |
| Sibling | Edward de Neville Lord Westmoreland (1409 - 1476) |
| Sibling | Ann de Neville Duchess of Buckingham ( - ) |
| Sibling | Catherine de Neville (1411 - 1469) |
| Sibling | Cecily de Neville (1415 - 1495) |
| Sibling | Edward de Neville Baron Abergavenny (1417 - 1476) |