| Father | King Toirdhealbhach Bog O'Brien King of Thomond (1395 - 1459) |
| Mother | Catherine De Burgh (1397 - 1480) |
| Sibling | King of Thomond Tadg an Chomaid O'Brien (1423 - 1466) |
| Sibling | Reynalda Ragnailt Ni Bhriain Thomond (1425 - 1510) |
| Sibling | Murchadh MacToirdhealbaig (1430 - ) |
| Sibling | Donnchadh macToirdhealbhaig O'Brien Bishop of Killaloe (1432 - 1502) |
| Sibling | Mathghamhain 'Tánaiste' macToirdhealbaig O'Brien (1436 - 1472) |
| Sibling | Mahon of Kilchaney Brien ( - 1474) |
| Sibling | Conchobhar Mór macToirdhealbhaig O'Brien King of Thomond ( - 1496) |
| Sibling | Brian Ganeagh Brien ( - ) |
| Sibling | Kennedy O'Brien ( - ) |