| Father | Henry Edward Watkins (1782 - 1856) |
| Mother | Agnes Woodson Venable (1796 - 1868) |
| Sibling | Francis Nathaniel Watkins (1813 - 1885) |
| Sibling | Henry Edward Watkins Jr (Dr) (1815 - 1917) |
| Sibling | Anne M. Watkins (1816 - ) |
| Sibling | Mary Cabell Watkins (1818 - 1912) |
| Sibling | Samuel Woodson Watkins Rev. (1819 - 1889) |
| Sibling | Agnes W. Watkins (1822 - 1922) |
| Sibling | Elizabeth A. Watkins (1825 - 1850) |
| Sibling | Richard Venable Watkins (1826 - 1905) |
| Sibling | Margaret C. Watkins (1828 - 1912) |
| Sibling | Henrietta Mattie Watkins (1830 - ) |
| Sibling | Frances Leigh "Fanny" Watkins (1834 - 1936) |