| Father | Francis Littlefield Sr (1619 - 1712) |
| Mother | Rebecca Rust (1630 - 1685) |
| Sibling | Capt. James Littlefield (1657 - 1690) |
| Sibling | Sarah Littlefield (1649 - 1734) |
| Sibling | Hannah Littlefield (1652 - 1692) |
| Sibling | Edmund Caleb Littlefield (1653 - 1718) |
| Sibling | Deliverance Littlefield (1655 - 1733) |
| Sibling | Issac Littlefield (1660 - 1676) |
| Sibling | Abigail Littlefield (1662 - 1718) |
| Sibling | Daniel Littlefield (1664 - 1718) |
| Sibling | Dorcas Littlefield (1664 - ) |
| Sibling | Rachel Littlefield (1666 - 1706) |
| Sibling | Phebe Littlefield (1670 - 1697) |
| Sibling | Dependence Littlefield (1671 - 1757) |