| Spouse | Maltby Gelstone Pierson (1790 - 1864) |
| Child | Harriet C Pierson (1839 - ) |
| Child | Mary Ann Pierson (1826 - 1909) |
| Child | Hannah M. Pierson (1826 - ) |
| Child | Julia B. Pierson (1837 - 1854) |
| Child | John M. Pierson (1829 - ) |
| Child | Allen H Pierson (1833 - 1864) |
| Child | Miss Pierson ( - ) |
| Child | Charles J Pierson ( - 1879) |
| Child | Sarah L Pierson (1832 - 1850) |
| Child | William Pierson (1835 - ) |
| Child | Ellen Elizabeth Pierson (1835 - 1864) |
| Child | Isaac N Pierson (1822 - ) |
| Child | Aaron Pierson (1823 - ) |
| Child | David L Pierson (1831 - ) |
| Child | Henry W Pierson (1827 - ) |
| Child | Maltby Geiburg Pierson (1834 - ) |