| Spouse | Mary Gustin (1751 - 1808) |
| Child | Lucy Mather (1795 - 1796) |
| Child | Leepha Mather (1793 - ) |
| Child | Leepha Mather (1793 - ) |
| Child | Samuel Mather (1791 - ) |
| Child | Augustine Mather (1790 - 1869) |
| Child | Augustus Mather (1789 - 1869) |
| Child | Caroline Mather (1785 - ) |
| Child | Buckley Mather (1785 - 1856) |
| Child | Jehoida Mather (1782 - 1847) |
| Child | Jehoida Mather (1782 - 1847) |
| Child | Lucinda Mather (1780 - 1852) |
| Child | Asaph Mather (1779 - 1859) |
| Child | Joshua Mather (1777 - 1854) |
| Child | Rebecca Mather (1775 - 1854) |
| Child | Mary Mather (1772 - 1851) |
| Child | Reuben Mather (1771 - 1859) |
| Child | Capt. John Mather (1783 - 1870) |
| Child | Samuel B. Mather (1791 - 1875) |