| Father | Robert Drake (1528 - 1600) |
| Mother | Elizabeth Prideaux (1523 - 1572) |
| Sibling | Amy Drake (1547 - ) |
| Sibling | Gertrude Drake (1563 - ) |
| Sibling | Mary Drake (1565 - 1650) |
| Sibling | Bernard Drake (1559 - 1596) |
| Sibling | John Drake (1549 - 1592) |
| Sibling | Elizabeth Maude Drake (1580 - 1670) |
| Sibling | Henry Drake (1555 - 1609) |
| Sibling | Nicholas Drake (1561 - 1640) |
| Sibling | William Drake (1553 - 1625) |
| Sibling | Robert Drake (1553 - 1604) |
| Sibling | John Robert Drake Sr. (1580 - 1651) |
| Sibling | Humphrey Capt Drake (1551 - 1604) |
| Sibling | Robert Drake (1553 - 1640) |
| Sibling | Joan Drake (1547 - 1596) |
| Sibling | Elizabeth Drake (1563 - ) |
| Sibling | Joan Drake (1548 - 1573) |
| Sibling | Mary Elmira Knight (1565 - 1650) |
| Sibling | John Drake (1549 - ) |