| Father | Daniel W. Worthington (1698 - 1784) |
| Mother | Elisabeth Loomis (1702 - 1789) |
| Sibling | Elizabeth Worthington (1721 - 1789) |
| Sibling | Elias Worthington (1722 - 1811) |
| Sibling | Asa Worthington (1724 - 1751) |
| Sibling | Sybil Worthington (1727 - 1828) |
| Sibling | Samuel Worthington (1729 - 1811) |
| Sibling | Rhoda Worthington (1730 - 1784) |
| Sibling | Mehitabel Worthington (1731 - 1742) |
| Sibling | Daniel Worthington (1734 - 1830) |
| Sibling | Jacob Worthington (1736 - 1763) |
| Sibling | Mary Worthington (1737 - 1829) |
| Sibling | Abigail Worthington (1740 - 1815) |
| Sibling | Amy Worthington (1741 - 1835) |
| Sibling | Mehitable Worthington (1742 - 1816) |
| Sibling | William Worthington (1743 - 1744) |
| Sibling | William Worthington Sr (1745 - 1825) |
| Sibling | Amasa Worthington (1746 - 1754) |