| Spouse | Mattie Winegine Gibbons (1853 - 1916) |
| Child | Marvin Hall Chamberlin (1885 - 1955) |
| Child | Alice Bertha D Chamberlin (1889 - 1980) |
| Child | (infant) Chamberlin (1873 - 1873) |
| Child | Catherine Chamberlin (1876 - 1878) |
| Child | Georgeanna Peral Chamberlin (1880 - 1895) |
| Child | Patty Chamberlin (1882 - 1882) |
| Child | Glenn Talbot Chamberlin (1883 - 1887) |
| Child | Benjamin Claude Chamberlin (1887 - 1888) |
| Child | (infant) Chamberlin (1891 - 1891) |
| Child | Una M Chamberlin (1893 - 1969) |
| Child | Claud Melnotte Chamberlin (1878 - 1953) |
| Child | Guy Bates Chamberlain (1874 - 1940) |