| Father | Major Duke (1747 - 1838) |
| Mother | Elizabeth Drury (1745 - 1820) |
| Sibling | Holly Ann Duke (1769 - 1838) |
| Sibling | Elizabeth Duke (1765 - 1878) |
| Sibling | Ann Duke (1765 - ) |
| Sibling | William Henry Duke (1766 - 1847) |
| Sibling | Priscilla Duke (1767 - 1860) |
| Sibling | Mary Duke (1769 - 1881) |
| Sibling | Sarah Duke (1770 - 1833) |
| Sibling | Margaret Duke (1774 - 1856) |
| Sibling | W Hardiman Duke (1774 - 1847) |
| Sibling | Alice Duke (1778 - 1878) |
| Sibling | Elizabeth Betsy Duke (1779 - 1878) |
| Sibling | Martha Patty "Patsy" Duke (1780 - 1860) |
| Sibling | Nancy Duke (1783 - 1850) |