| Father | William Thomas Ayers (1790 - 1836) |
| Mother | Catharine Yates (1790 - 1881) |
| Sibling | Samuel Lemuel Ayers (1800 - 1860) |
| Sibling | Uriah Hugh Ayers (1815 - 1880) |
| Sibling | James Jackson Ayers (1815 - 1898) |
| Sibling | Effa Ayers (1819 - ) |
| Sibling | Thomas Andrew Ayers Sr (1820 - 1890) |
| Sibling | Iwanowna Ayers (1821 - 1888) |
| Sibling | Joshua A Ayers (1823 - 1843) |
| Sibling | Joel Thomas Ayers Sr. (1827 - 1901) |
| Sibling | Rachel Parthenia Ayers (1831 - 1915) |
| Sibling | John Jefferson Ayers (1838 - 1926) |
| Sibling | Andrew J Ayers (1840 - 1863) |
| Sibling | Mittie Yates (1840 - ) |