| Spouse | Jane Hawkins (1688 - 1796) |
| Child | Lucy Gholson (1734 - 1795) |
| Child | Martha Collins (1720 - 1781) |
| Child | Elizabeth Gholson (1732 - ) |
| Child | Samuel Gholson (1772 - 1852) |
| Child | Dorothy Gholson (1786 - 1827) |
| Child | Mary Kingstone ( - ) |
| Child | Elijah Gholson (1710 - ) |
| Child | Sarah Gholson (1714 - ) |
| Child | Sarah Gholson (1752 - ) |
| Child | William Anthony Gholston (1705 - 1779) |
| Child | Eleanor Kingstone ( - ) |
| Child | John Gholson (1713 - 1790) |
| Child | William Gholson (1728 - 1808) |
| Child | Daughter Gholson ( - ) |
| Child | William Anthony Gholson (1762 - 1843) |